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Ctbp-interacting protein

WebMar 23, 2024 · A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3. ... Frisch, S. M., Goodman, R. H. Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. Cell 115: 177-186, 2003. ... WebJan 24, 2024 · CtIP Antibody (D-4) is an IgG 2b κ mouse monoclonal CtIP antibody (also designated RB Binding Protein 8 antibody, Retinoblastoma-Binding Protein 8 antibody, …

Interaction of MEQ protein and C-terminal-binding protein is …

WebCtIP is a transcriptional co-regulator that binds a number of proteins involved in cell cycle control and cell development, such as CtBP (Cterminus-binding protein), BRCA1 (breast … WebOct 23, 2024 · Abstract Human C-terminal binding protein (CtBP)-interacting protein (CtIP) is a central regulator to initiate DNA end resection and homologous recombination (HR). Several studies have shown that post-translational modifications control the activity or expression of CtIP. ebook writers for hire https://theuniqueboutiqueuk.com

Double-strand break repair: 53BP1 comes into focus

WebNov 2, 2024 · CtBP2 represses Forkhead box O1 (FoxO1)-mediated hepatic gluconeogenesis directly as well as Sterol Regulatory Element-Binding Protein 1 (SREBP1)-mediated lipogenesis indirectly. The activity of... WebJul 1, 2024 · Human C-terminal-binding protein 1 (CtBP1) was initially identified as a phospho-protein that bound a short Pro-Leu-Asp-Leu-Ser (PLDLS) region in the C … ebook writing free

The role of CtBP1 in oncogenic processes and its potential as a ...

Category:BRG1 Protein - an overview ScienceDirect Topics

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Ctbp-interacting protein

The transcriptional corepressor CtBP2 serves as a metabolite …

WebJun 15, 2012 · CtIP (CtBP-interacting protein) associates with BRCA1 and the Mre11-Rad50-Nbs1 (MRN) complex and plays an essential role in homologous … WebJan 29, 2009 · Recent work from the laboratories of Grossman and Lewis ( 16, 25, 26) indicate that CtBP is a direct target for the Ink4a/Arf tumor suppressor. Attempts to …

Ctbp-interacting protein

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WebNov 2, 2024 · Here we describe a hepatic system in this context orchestrated by the transcriptional corepressor C-terminal binding protein 2 (CtBP2) that harbors metabolite … WebApr 7, 2024 · The middle HD region is flanked by the Smad interaction domain (SID) and the C-terminal binding protein (CtBP)-interaction domain (CID) [ 27 ]. These interaction domains are instrumental in recruiting additional proteins with the capability to control ZEB1′s transcriptional activity [ 25 ].

WebApr 7, 2024 · The middle HD region is flanked by the Smad interaction domain (SID) and the C-terminal binding protein (CtBP)-interaction domain (CID) . These interaction … WebOct 17, 2003 · Like other E1A binding proteins, CtBP also interacts with a wide variety of cellular factors, many of which have been characterized as DNA binding transcriptional repressors ( Chinnadurai 2002 ). Thus, CtBP …

WebApr 9, 2024 · Summary. This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may … WebMay 1, 2024 · Typical for multivalent adaptor proteins, CtIP contains various short linear sequence motifs facilitating interactions between protein-binding partners, some of which are governed by CtIP phosphorylation (Fig. 1) [2, 24].For instance, CDK-mediated phosphorylation of CtIP at S327 is a prerequisite for the binding of BRCA1 BRCT …

WebJan 30, 2006 · Most of the factors that interact with CtBP are transcriptional regulators and bind to CtBP through a conserved Pro-X-Asp-Leu-Ser (“PXDLS”) CtBP-binding domain that is necessary and probably sufficient for the interaction (11, 12).It has recently been shown that CtBP-containing protein complexes include several factors that coordinate …

WebAug 1, 2015 · The CtBP (C-terminal binding protein) interacting protein (CtIP) was initially identified as part of the CtBP transcriptional corepressor complex that mediates … compiled works dezno banWebStructural and Functional Analyses of CtBP. The crystal structures of the N-terminal two-thirds of both human CtBP1/2 (16, 17) and rat CtBP/BARS have been solved, providing … ebook writer software freeWebFeb 11, 2005 · Carboxyl-terminal binding protein (CtBP) is a transcriptional corepressor that interacts with a wide variety of cellular factors and carries out important functions in development, cell-cycle regulation, and transformation ().Microarray assays of mouse embryo fibroblasts (MEFs) derived from animals engineered to contain mutations in the … ebook writing format