Web13 apr 2024 · Purpose To understand how surfactants affect drug release from ternary amorphous solid dispersions (ASDs), and to investigate different mechanisms of … Web1 giu 2024 · Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been employed to produce ASDs and novel...
Recent Technologies for Amorphization of Poorly Water-Soluble …
Web5 dic 2024 · Designing co-amorphous formulations is now recognized as a relevant strategy for improving the bioavailability of low-molecular-weight drugs. In order to determine the most suitable low-molecular-weight excipients for stabilizing the drug in the amorphous state, screening methods were developed mostly using amino acids as co-formers. Web16 mar 2024 · Drug crystal growth in ternary amorphous solid dispersions: effect of surfactants and polymeric matrix-carriers Int. J. Pharm. X , 3 ( 2024 ) , Article 100086 , 10.1016/j.ijpx.2024.100086 View PDF View article View in Scopus Google Scholar briarstone hoa
Why Amorphous Drugs? SpringerLink
WebHowever, the amorphous form tends to recrystallize on storage, which limits the benefits of this approach. Specific interactions between the drug and the polymer may retard this … Web19 ago 2014 · Principal Scientist. Lonza. Mar 2016 - Present7 years 2 months. Bend, Oregon. • Leads research initiatives to develop novel … Web30 mar 2024 · Dissolution of amorphous solid dispersions (ASD) can lead to the formation of amorphous drug-rich nano species (nanodroplets) via liquid–liquid phase separation or glass–liquid phase separation when the … coventry blaze live twitter