WebPotent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal … Web1 feb. 2000 · Calcium ionophore (CaI) A23187 is a compound commonly used in research to increase intracellular calcium. This substance has been shown to be able to activate …
Murine CD4+CD25- cells activated in vitro with PMA/ionomycin …
WebIonomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Data Sheet Citations WebElevating intracellular [Ca 2+] with the ionophore A23187 or ionomycin or with the tumor promoter thapsigargin mimicked the effects of hormones on tyrosine phosphorylation, whereas treatment with a PKC-activating phorbol ester did not. In addition, responses to angiotensin II were not diminished in PKC-depleted cells. phone shop ashby
Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells
Web24 jan. 2024 · These results suggested that using different types of calcium ionophore (ionomycin and calcimycin) for AOA would not increase the incidence of birth defects in … Webresponse to ionizing radiation, low concentrations of hydrogen peroxide, and the Ca2+ ionophore ionomycin.” Presented at the 94th Annual American Association for Cancer Research meeting held in ... WebThe aim of this study is to assess the in vitro contractility of humanoid AAA and non-pathologic major SMC. Biopsies were perioperatively harvested from AAA sufferers (n = 21) and operation (n = 6) and clinical data were collected. Contractility was measured using Electric Cell-substrate Impedance Scanner (ECIS) upon ionomycin stimulation. phone shop armley town street