Iron-sulfur cluster-binding protein ykgf

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August undefined, 2024

WebBinding site: 111 [4Fe-4S] cluster 1 (UniProtKB ChEBI) PROSITE-ProRule annotation. Sequence: C: Binding site: 114 ... PTHR10849 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL 1 hit; PROSITE. View protein in PROSITE; PS00198 4FE4S_FER_1 2 hits; PS51379 4FE4S_FER_2 2 hits; Pfam. View protein in Pfam; WebIron–sulfur (Fe/S) clusters (ISCs) are redox-active protein cofactors that their synthesis, transfer, and insertion into target proteins require many components. Mitochondrial ISC …

An iron–sulfur grip Nature Chemical Biology

WebIron-sulfur cluster proteins participate in the control of gene expression, oxygen/nitrogen sensing, control of labile iron pool and DNA damage recognition and repair. Their role in … WebIron-sulfur (Fe-S) clusters are present in more than 200 different types of enzymes or proteins and constitute one of the most ancient, ubiquitous and structurally diverse classes of biological prosthetic groups. Hence the process of Fe-S cluster biosynthesis is … The central theme of all three Fe-S cluster assembly systems is cysteine … The cytosolic iron-sulfur (Fe-S) assembly (CIA) pathway is required for the … css on scr

ykgF:Gene Product(s) - EcoliWiki

WebJul 23, 2024 · The relevance of this approach is still testified by (1) its wide use to reconstitute iron-sulfur proteins as shown by papers in recent years: ISCU , Chromokinesin, KIF4A , FNR, and NsrR , and (2) the ability to carry out eukaryotic Fe-S cluster reconstitution by the well-characterized prokaryotic systems and/or its essential components such as ... WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) WebIron-sulfur clusters have a remarkable facility for conversion and interconversion in both the free and protein-bound conditions, supporting the concept that they are modular structures. They also undergo ligand exchange reactions and oxidative degradation, both of which are biologically significant. css on sharepoint online

Iron-Sulfur Cluster Biosynthesis - RCSB: PDB-101

WebDOI: 10.1016/j.tem.2009.12.006 Abstract Iron-sulfur (Fe/S) proteins are a class of ubiquitous components that assist in vital and diverse biochemical tasks in virtually every living cell. These tasks include respiration, iron homeostasis and gene expression. Webthan a [2Fe-2S] cluster. The site-directed mutation experi-ments suggest that the four cysteine residues are involved in the ligation of this [4Fe-4S] cluster. This iron-sulfur cluster has a unique feature, very high sensitivity to oxygen exposure, which has not been observed on other EPR-detectable iron-sulfur clusters in NDH-1/complex I. earl shibe painting locationsWeb2 days ago · Introduction. Iron is an essential trace element that functions as a cofactor in a wide variety of biological processes, such as oxygen delivery, ATP production, and DNA synthesis and repair, by binding to proteins (1, 2).However, excess iron is toxic owing to its ability to promote the generation of reactive oxygen species (3, 4).Ferroptosis (5), a type … csso obt 0.11

"WebJul 23, 2024 · When the iron salt is dissolved, adjust the volume to 10 mL ( see Note 7 ). 2. Fe dilution: 1 mM ammonium iron ( ii) sulfate ( (NH 4) 2 Fe (SO 4) 2 ·6H 2 O). Add 25 μL of … " - Iron-sulfur cluster-binding protein ykgf

Iron-sulfur cluster-binding protein ykgf

Iron-Sulfur Cluster - an overview ScienceDirect Topics

WebNov 5, 2024 · IscR (iron-sulfur cluster regulator) is an iron-dependent regulator of isc-suf genes and other genes with a role in iron metabolism. ... Gel-retardation assays showed the binding of regulatory proteins to individual promoters. Our results demonstrated that several promoters in a sense and antisense direction influenced isc-suf expression and ...

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WebIron-sulfur clusters-containing proteins participate in many cellular processes, including crucial biological events like DNA synthesis and processing of dioxygen. In most iron … WebNational Center for Biotechnology Information

WebIron-sulfur clusters are perfect for this task, since they form a unique delocalized system for storing an electron that may be tuned by the surrounding amino acids in a protein. Two types of clusters are particularly common: a square arrangement of two irons and two sulfurs, and a distorted cube composed of four irons and four sulfurs. Iron–sulfur clusters are molecular ensembles of iron and sulfide. They are most often discussed in the context of the biological role for iron–sulfur proteins, which are pervasive. Many Fe–S clusters are known in the area of organometallic chemistry and as precursors to synthetic analogues of the biological clusters (see Figure). It is believed that the last universal common an…

WebFeb 8, 2024 · Chestnut Hill, Mass. (2/8/2024) – Boston College chemists have developed a strategy to monitor the presence or absence of iron-sulfur clusters, which are essential to the function of diverse... WebGene ID: 56560881, updated on 7-Feb-2024. Summary Other designations. 2Fe-2S iron-sulfur cluster binding domain-containing protein

WebGO:0051536 ! iron-sulfur cluster binding GO:0051539 ! 4 iron, 4 sulfur cluster binding GO:0055114 ! oxidation-reduction process GO:0003674 ! molecular function GO:0005575 ! …

WebFeb 8, 2024 · The iron-sulfur (Fe-S) proteomic platform the team developed allowed them to gain a greater insight into the dynamics of iron-sulfur cluster delivery and binding, according to Professor of... css on top of everythingWebOct 19, 2024 · Our data indicate that the iron-sulfur cluster is critical for interaction of human Polε with DNA. Probably, abrogated DNA binding is responsible for the loss of both activities in hPolε CD.... earl shibe colorsWebOct 19, 2024 · Our data indicate that the iron-sulfur cluster is critical for interaction of human Polε with DNA. Probably, abrogated DNA binding is responsible for the loss of … earl shibe painting costWebIron–sulfur clusters are ubiquitous in modern biological systems, serving multiple purposes including protein structural stabilization, electron transfer, substrate binding and … earls hideaway hotelsWebAbstract. Iron–sulfur clusters are ubiquitous and ancient prosthetic groups that are present in all kingdoms of life. They are flexible in terms of coordination and redox properties. The … earl shibe painting specialsWebJan 31, 2024 · Iron sulfur proteins (Fe-S) are ancient structures present in archaebacteria and are involved in central metabolic functions in these ancient organisms (Iwasaki, Archaea 2010:1, 2010). From an evolutionary perspective, Fe-S clusters originated early on during protein evolution; with the aid of an inducible and robust antioxidant defense system ... css on touchWebJul 31, 2024 · Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. css -o-object-fit